Active Ingredient: Tadalafil
Indication: Cialis 5mg is indicated for the treatment of erectile dysfunction (ED) in adult men. It is also prescribed for the management of symptoms of benign prostatic hyperplasia (BPH) in men with or without ED.
Mechanism of Action: Tadalafil, the active ingredient in Cialis, works by inhibiting the enzyme phosphodiesterase type 5 (PDE5), which is responsible for the degradation of cyclic guanosine monophosphate (cGMP) in the corpus cavernosum of the penis. Inhibition of PDE5 leads to increased levels of cGMP, which relaxes smooth muscles in the blood vessels of the penis, allowing for increased blood flow and thus, improved erectile function.
Dosage and Administration: Cialis 5mg is typically taken orally, with or without food, as directed by a healthcare provider. The recommended starting dose for most men is 5mg once daily, taken at approximately the same time each day. However, dosage may be adjusted based on individual response and tolerability. Cialis should not be taken more than once per day.
Onset and Duration of Action: Cialis 5mg has a relatively rapid onset of action, with effects typically observed within 30 minutes to 1 hour after administration. The medication remains effective for up to 36 hours, earning it the nickname "the weekend pill."
Contraindications: Cialis 5mg is contraindicated in individuals with a known hypersensitivity to tadalafil or any component of the medication. It should not be used concurrently with nitrates or alpha-blockers, as this may potentiate hypotensive effects. Patients with severe hepatic impairment or end-stage renal disease requiring dialysis should also avoid its use.
Adverse Reactions: Common adverse reactions associated with Cialis 5mg include headache, dyspepsia, back pain, myalgia, nasal congestion, flushing, and dizziness. Rare but serious adverse reactions may include priapism (prolonged erection), sudden hearing loss, and vision changes.
Precautions: Patients should be advised to seek immediate medical attention if an erection persists for more than 4 hours, as priapism can result in permanent damage to the penis. Caution is advised in patients with a history of cardiovascular disease, as sexual activity may pose a risk. Use of alcohol and grapefruit juice should be limited while taking Cialis, as they may increase the risk of adverse effects.
Interactions: Cialis 5mg may interact with certain medications, including nitrates, alpha-blockers, antihypertensives, antifungals, antibiotics, and HIV protease inhibitors. Patients should inform their healthcare provider of all medications, supplements, and herbal products they are taking before starting Cialis therapy.
Storage: Cialis 5mg should be stored at room temperature, away from moisture and heat. Keep the medication out of reach of children.
Disclaimer: This information is not intended as medical advice. Always consult a healthcare professional for personalized guidance and treatment recommendations.